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MAPK3 - TOP2A
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
MAPK3
ENSG00000102882
No diseases in record
No drugs in record
phosphotyrosine residue binding
protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
kinase activity
phosphatase binding
scaffold protein binding
FUS3 (S. cerevisiae)
KSS1 (S. cerevisiae)
mpk-1 (C. elegans)
rl (D. melanogaster)
TOP2A
ENSG00000131747
No diseases in record
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)