Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
POLD1
|
ENSG00000062822
|
CRC
|
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
|
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5'-exodeoxyribonuclease activity
enzyme binding
metal ion binding
4 iron, 4 sulfur cluster binding
|
POL3 (S. cerevisiae)
F10C2.4 (C. elegans)
DNApol-delta (D. melanogaster)
|
PMS2
|
ENSG00000122512
|
colorectal
endometrial
ovarian
medulloblastoma
glioma
|
No drugs in record
|
DNA binding
endonuclease activity
protein binding
ATP binding
ATPase activity
single base insertion or deletion binding
single-stranded DNA binding
MutSalpha complex binding
mismatched DNA binding
|
PMS1 (S. cerevisiae)
Pms2 (D. melanogaster)
|