NEDD4 - APEX1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NEDD4	ENSG00000069869	No diseases in record	No drugs in record	protein binding sodium channel inhibitor activity protein domain specific binding beta-2 adrenergic receptor binding ionotropic glutamate receptor binding ubiquitin binding phosphoserine residue binding phosphothreonine residue binding ubiquitin protein ligase activity RNA polymerase binding proline-rich region binding ubiquitin-protein transferase activity Notch binding myosin binding	RSP5 (S. cerevisiae) Nedd4 (D. melanogaster)
APEX1	ENSG00000100823	No diseases in record	No drugs in record	DNA binding damaged DNA binding double-stranded telomeric DNA binding transcription coactivator activity transcription corepressor activity DNA-(apurinic or apyrimidinic site) lyase activity endonuclease activity endodeoxyribonuclease activity RNA-DNA hybrid ribonuclease activity phosphodiesterase I activity uracil DNA N-glycosylase activity protein binding phosphoric diester hydrolase activity double-stranded DNA exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity 3'-5' exonuclease activity oxidoreductase activity site-specific endodeoxyribonuclease activity, specific for altered base chromatin DNA binding protein complex binding metal ion binding NF-kappaB binding	APN2 (S. cerevisiae) exo-3 (C. elegans) Rrp1 (D. melanogaster)