HIF1A - DNA2

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HIF1A	ENSG00000100644	endometrioid carcinoma glioblastoma colorectal renal lung pancreatic	No drugs in record	transcription factor activity, transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding enzyme binding protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding nuclear hormone receptor binding histone deacetylase binding protein heterodimerization activity Hsp90 protein binding sequence-specific DNA binding	hif-1 (C. elegans)
DNA2	ENSG00000138346	No diseases in record	No drugs in record	DNA binding DNA helicase activity helicase activity nuclease activity protein binding ATP binding ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity metal ion binding 4 iron, 4 sulfur cluster binding catalytic activity ATP-dependent DNA helicase activity single-stranded DNA endodeoxyribonuclease activity nucleotide binding hydrolase activity iron-sulfur cluster binding chromatin binding 5' overhang single-stranded DNA endodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity	DNA2 (S. cerevisiae) dna-2 (C. elegans) CG2990 (D. melanogaster)