CDC6 - HMGB1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDC6	ENSG00000094804	No diseases in record	No drugs in record	nucleotide binding protein binding ATP binding kinase binding ATPase activity GTP binding GTPase activity chromatin binding DNA replication origin binding DNA-directed DNA polymerase activity 3'-5' exonuclease activity metal ion binding 4 iron, 4 sulfur cluster binding DNA binding	CDC6 (S. cerevisiae) Cdc6 (D. melanogaster)
HMGB1	ENSG00000189403	No diseases in record	No drugs in record	four-way junction DNA binding bubble DNA binding lipopolysaccharide binding phosphatidylserine binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity protein binding transcription factor binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity RAGE receptor binding DNA polymerase binding repressing transcription factor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)