SYK - HMGB1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SYK	ENSG00000165025	MDS peripheral T-cell lymphoma	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity integrin binding protein binding ATP binding protein kinase binding phosphatase binding Toll-like receptor binding	No GO terms in record
HMGB1	ENSG00000189403	No diseases in record	No drugs in record	four-way junction DNA binding bubble DNA binding lipopolysaccharide binding phosphatidylserine binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity protein binding transcription factor binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity RAGE receptor binding DNA polymerase binding repressing transcription factor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)