REV3L - KDR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
REV3L	ENSG00000009413	No diseases in record	No drugs in record	nucleotide binding DNA binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity metal ion binding 4 iron, 4 sulfur cluster binding	REV3 (S. cerevisiae) mus205 (D. melanogaster)
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)