KDM5C - KDM6A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM5C	ENSG00000126012	clear cell renal carcinoma	No drugs in record	DNA binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors histone demethylase activity histone demethylase activity (H3-K4 specific)	JHD2 (S. cerevisiae) rbr-2 (C. elegans)
KDM6A	ENSG00000147050	renal cell carcinoma bladder carcinoma oesophageal SCC MM medulloblastoma T-ALL other tumour types	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding chromatin DNA binding histone demethylase activity identical protein binding metal ion binding dioxygenase activity histone demethylase activity (H3-K27 specific)	CYC8 (S. cerevisiae) Utx (D. melanogaster)