MAP3K4 - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP3K4	ENSG00000085511	No diseases in record	No drugs in record	MAP kinase kinase kinase activity protein binding ATP binding metal ion binding	SSK2 (S. cerevisiae) SSK22 (S. cerevisiae) drl-1 (C. elegans) Mekk1 (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)