Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
KDR
|
ENSG00000128052
|
NSCLC
angiosarcoma
melanoma
|
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
|
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
|
Pvr (D. melanogaster)
|
ACTL6A
|
ENSG00000136518
|
No diseases in record
|
No drugs in record
|
chromatin binding
transcription coactivator activity
protein binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
|
ARP4 (S. cerevisiae)
swsn-6 (C. elegans)
Bap55 (D. melanogaster)
|