Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
FGFR1
|
ENSG00000077782
|
MPN
NHL
salivary adenoma
|
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
|
protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
heparin binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
identical protein binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
egl-15 (C. elegans)
htl (D. melanogaster)
|
SMAD2
|
ENSG00000175387
|
colorectal carcinoma
hepatocellular carcinoma
|
No drugs in record
|
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
transcription factor binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
ubiquitin protein ligase binding
activating transcription factor binding
type I transforming growth factor beta receptor binding
enhancer binding
protein homodimerization activity
SMAD binding
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding
R-SMAD binding
DNA binding
|
sma-3 (C. elegans)
sma-2 (C. elegans)
|