AXIN1 - PDGFRB

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
AXIN1 ENSG00000103126 colorectal
endometrial
prostate
hepatocellular carcinoma
hepatoblastoma
sporadic medulloblastoma

No drugs in record

signal transducer activity
GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
receptor signaling complex scaffold activity
ubiquitin protein ligase binding
protein complex scaffold activity
identical protein binding
protein homodimerization activity
SMAD binding
armadillo repeat domain binding
I-SMAD binding
Axn (D. melanogaster)
PDGFRB ENSG00000113721 MPN
AML
CMML
CML
BECAPLERMIN
DASATINIB
IMATINIB
NINTEDANIB
PAZOPANIB
REGORAFENIB
SORAFENIB
SUNITINIB
protein tyrosine kinase activity
platelet activating factor receptor activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
enzyme binding
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)