KEAP1 - NFE2L2

H. sapiens

SSL interaction

 CSNK2A1 NFE2L2 CREBBP BRCA1 UBE2I HSP90AB1 PCNA EP300 AKT1 IKBKB UBB ESR1 HSP90AA1 UBC SP1 HIF1A TP53 MAPK14 FYN MAPK1 SIRT1 FBXW7 RB1 PDGFRB CDKN1B FHOD1 ABL1 KEAP1 MBNL1 BIRC8 LITAF CTNND2 PTK6 MAPKAPK2 RFX1 PDZD3 EIF1AD MX1 HDAC6 SESN2 LARP4B LCMT1 PAK5 CDC42BPA ENSA FES TCF7 ITGA1 KLC3 NR1D1 TAOK3 ZDHHC17 SOCS5

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
KEAP1 ENSG00000079999 NSCLC
breast carcinoma
DIMETHYL FUMARATE
protein binding
transcription factor binding
ubiquitin-protein transferase activity
actin binding
protein homodimerization activity
Keap1 (D. melanogaster)
NFE2L2 ENSG00000116044 NSCLC
HNSCC

No drugs in record

transcription regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription cofactor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
transcription regulatory region DNA binding
cnc (D. melanogaster)