RAPGEF1 - KDR

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
RAPGEF1 ENSG00000107263

No diseases in record

No drugs in record

protein binding
Rap guanyl-nucleotide exchange factor activity
SH3 domain binding
CDC25 (S. cerevisiae)
C3G (D. melanogaster)
KDR ENSG00000128052 NSCLC
angiosarcoma
melanoma
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
Pvr (D. melanogaster)