PDGFRB - TIAM1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
TIAM1	ENSG00000156299	No diseases in record	No drugs in record	signal transducer activity, downstream of receptor guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding microtubule binding lipid binding kinase binding Rac guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding Rac GTPase binding	No GO terms in record