BTK - MRE11

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
BTK ENSG00000010671 CLL
mantle cell lymphoma
WM
IBRUTINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
identical protein binding
metal ion binding
receptor binding
Btk29A (D. melanogaster)
MRE11 ENSG00000020922

No diseases in record

No drugs in record

hydrolase activity
exonuclease activity
endonuclease activity
protein complex scaffold activity
manganese ion binding
nuclease activity
3'-5' exonuclease activity
G-quadruplex DNA binding
single-stranded telomeric DNA binding
double-stranded telomeric DNA binding
telomeric DNA binding
endodeoxyribonuclease activity
adenylate kinase activity
protein binding
DNA end binding
single-stranded DNA endodeoxyribonuclease activity
Y-form DNA binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
MRE11 (S. cerevisiae)
mre-11 (C. elegans)