BTK - TOP2B

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BTK	ENSG00000010671	CLL mantle cell lymphoma WM	IBRUTINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding identical protein binding metal ion binding receptor binding	Btk29A (D. melanogaster)
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)