PKN1 - GRB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PKN1	ENSG00000123143	No diseases in record	No drugs in record	chromatin binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity protein kinase C binding protein binding ATP binding GTP-Rho binding ligand-dependent nuclear receptor transcription coactivator activity histone kinase activity (H3-T11 specific) histone binding histone deacetylase binding Rac GTPase binding androgen receptor binding	PKC1 (S. cerevisiae) pkn-1 (C. elegans) Pkn (D. melanogaster)
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)