CHEK2 - WT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHEK2	ENSG00000183765	breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding	RAD53 (S. cerevisiae) chk-2 (C. elegans) T08D2.7 (C. elegans) lok (D. melanogaster)
WT1	ENSG00000184937	Wilms tumour desmoplastic small round cell tumour	No drugs in record	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding RNA binding protein binding zinc ion binding double-stranded methylated DNA binding sequence-specific DNA binding transcription regulatory region DNA binding hemi-methylated DNA-binding C2H2 zinc finger domain binding	MIG1 (S. cerevisiae) MIG2 (S. cerevisiae) MIG3 (S. cerevisiae)