PIN1 - MAP2K1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIN1	ENSG00000127445	No diseases in record	No drugs in record	peptidyl-prolyl cis-trans isomerase activity motor activity protein binding beta-catenin binding mitogen-activated protein kinase kinase binding GTPase activating protein binding phosphoserine residue binding phosphothreonine residue binding	ESS1 (S. cerevisiae) dod (D. melanogaster) CG32845 (D. melanogaster)
MAP2K1	ENSG00000169032	NSCLC melanoma colorectal	TRAMETINIB	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine phosphatase activity protein binding ATP binding protein C-terminus binding protein kinase binding protein serine/threonine kinase activator activity protein N-terminus binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)