ATM - FEN1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)
FEN1 ENSG00000168496 breast cancer

No drugs in record

magnesium ion binding
DNA binding
damaged DNA binding
double-stranded DNA binding
endonuclease activity
RNA-DNA hybrid ribonuclease activity
exonuclease activity
protein binding
double-stranded DNA exodeoxyribonuclease activity
5'-3' exonuclease activity
5'-flap endonuclease activity
flap endonuclease activity
nuclease activity
RAD27 (S. cerevisiae)
crn-1 (C. elegans)