PCNA - PTEN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PCNA	ENSG00000132646	No diseases in record	No drugs in record	purine-specific mismatch base pair DNA N-glycosylase activity chromatin binding damaged DNA binding protein binding enzyme binding estrogen receptor binding DNA polymerase processivity factor activity receptor tyrosine kinase binding dinucleotide insertion or deletion binding MutLalpha complex binding histone acetyltransferase binding identical protein binding DNA polymerase binding DNA binding	POL30 (S. cerevisiae) PCNA (D. melanogaster)
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)