Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
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Orthologs
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ESR1
|
ENSG00000091831
|
breast
|
BAZEDOXIFENE
DIENESTROL
DIETHYLSTILBESTROL
DIETHYLSTILBESTROL DIPHOSPHATE
ENCLOMIPHENE
ESTRADIOL
ESTRADIOL ACETATE
ESTRADIOL CYPIONATE
ESTRADIOL VALERATE
ESTROGENS, CONJUGATED
ESTROGENS, CONJUGATED SYNTHETIC A
ESTROGENS, ESTERIFIED
ESTRONE
ESTRONE SULFURIC ACID
ETHINYL ESTRADIOL
FULVESTRANT
MESTRANOL
OSPEMIFENE
POLYESTRADIOL PHOSPHATE
QUINESTROL
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B
TAMOXIFEN
TOREMIFENE
|
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
steroid binding
protein binding
beta-catenin binding
transcription factor binding
zinc ion binding
enzyme binding
nitric-oxide synthase regulator activity
estrogen receptor activity
estrogen response element binding
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
identical protein binding
ATPase binding
|
No GO terms in record
|
MAP2K2
|
ENSG00000126934
|
NSCLC
melanoma
|
TRAMETINIB
|
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
PDZ domain binding
protein serine/threonine kinase activator activity
metal ion binding
scaffold protein binding
|
PBS2 (S. cerevisiae)
mek-2 (C. elegans)
Dsor1 (D. melanogaster)
|