ERBB2 - PDIA3

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ERBB2 ENSG00000141736 breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity
growth factor binding
let-23 (C. elegans)
Egfr (D. melanogaster)
PDIA3 ENSG00000167004

No diseases in record

No drugs in record

protein disulfide isomerase activity
cysteine-type endopeptidase activity
phospholipase C activity
protein binding
disulfide oxidoreductase activity
EUG1 (S. cerevisiae)
PDI1 (S. cerevisiae)
pdi-3 (C. elegans)
ERp60 (D. melanogaster)