PDGFRB - PIF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
PIF1	ENSG00000140451	No diseases in record	No drugs in record	magnesium ion binding ATP binding telomerase inhibitor activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent 5'-3' DNA/RNA helicase activity telomeric DNA binding ATP-dependent 5'-3' DNA helicase activity G-quadruplex DNA binding hydrolase activity nucleotide binding helicase activity single-stranded DNA binding DNA helicase activity DNA binding	PIF1 (S. cerevisiae) RRM3 (S. cerevisiae)