ARX - MRE11

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARX	ENSG00000004848	No diseases in record	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding nucleic acid binding	hbn (D. melanogaster)
MRE11	ENSG00000020922	No diseases in record	No drugs in record	hydrolase activity exonuclease activity endonuclease activity protein complex scaffold activity manganese ion binding nuclease activity 3'-5' exonuclease activity G-quadruplex DNA binding single-stranded telomeric DNA binding double-stranded telomeric DNA binding telomeric DNA binding endodeoxyribonuclease activity adenylate kinase activity protein binding DNA end binding single-stranded DNA endodeoxyribonuclease activity Y-form DNA binding single-stranded DNA 3'-5' exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity	MRE11 (S. cerevisiae) mre-11 (C. elegans)