Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
TOP2A
|
ENSG00000131747
|
No diseases in record
|
DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
|
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
|
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
|
REPS2
|
ENSG00000169891
|
No diseases in record
|
No drugs in record
|
calcium ion binding
protein binding
|
EDE1 (S. cerevisiae)
reps-1 (C. elegans)
Reps (D. melanogaster)
|