SMAD7 - CHD4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD7	ENSG00000101665	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding collagen binding beta-catenin binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding transcription regulatory region DNA binding metal ion binding activin binding I-SMAD binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)
CHD4	ENSG00000111642	uterine serous carcinoma	No drugs in record	RNA polymerase II repressing transcription factor binding DNA binding ATP-dependent DNA helicase activity histone deacetylase activity protein binding ATP binding microtubule binding zinc ion binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	CHD1 (S. cerevisiae) let-418 (C. elegans) chd-3 (C. elegans)