GSK3B - HMGB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GSK3B	ENSG00000082701	No diseases in record	LITHIUM CARBONATE LITHIUM CITRATE	RNA polymerase II transcription factor binding p53 binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding beta-catenin binding kinase activity protein kinase binding ubiquitin protein ligase binding protein kinase A catalytic subunit binding tau-protein kinase activity NF-kappaB binding	MRK1 (S. cerevisiae) RIM11 (S. cerevisiae) gsk-3 (C. elegans) sgg (D. melanogaster) gskt (D. melanogaster)
HMGB1	ENSG00000189403	No diseases in record	No drugs in record	four-way junction DNA binding bubble DNA binding lipopolysaccharide binding phosphatidylserine binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity protein binding transcription factor binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity RAGE receptor binding DNA polymerase binding repressing transcription factor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)