GATA1 - VAV1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GATA1	ENSG00000102145	megakaryoblastic leukaemia of Downs syndrome	No drugs in record	transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding DNA binding, bending chromatin DNA binding sequence-specific DNA binding C2H2 zinc finger domain binding	DAL80 (S. cerevisiae) GLN3 (S. cerevisiae) GZF3 (S. cerevisiae)
VAV1	ENSG00000141968	T-cell lymphoma	No drugs in record	transcription factor activity, sequence-specific DNA binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	CDC24 (S. cerevisiae)