PICALM - CTNNB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PICALM	ENSG00000073921	T-ALL AML	No drugs in record	protein binding 1-phosphatidylinositol binding clathrin binding clathrin heavy chain binding clathrin adaptor activity cadherin binding involved in cell-cell adhesion	YAP1801 (S. cerevisiae) YAP1802 (S. cerevisiae) unc-11 (C. elegans) lap (D. melanogaster)
CTNNB1	ENSG00000168036	colorectal ovarian hepatoblastoma pleomorphic salivary gland adenoma other tumour types	No drugs in record	RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity signal transducer activity protein binding protein C-terminus binding transcription factor binding enzyme binding kinase binding protein kinase binding protein phosphatase binding estrogen receptor binding nuclear hormone receptor binding transcription regulatory region DNA binding ion channel binding alpha-catenin binding cadherin binding SMAD binding protein heterodimerization activity androgen receptor binding I-SMAD binding repressing transcription factor binding cadherin binding involved in cell-cell adhesion euchromatin binding	bar-1 (C. elegans) hmp-2 (C. elegans) arm (D. melanogaster)