CASP8 - ARFGEF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
ARFGEF1	ENSG00000066777	No diseases in record	No drugs in record	guanyl-nucleotide exchange factor activity ARF guanyl-nucleotide exchange factor activity protein binding myosin binding protein kinase A regulatory subunit binding GTPase activator activity	SEC7 (S. cerevisiae) Sec71 (D. melanogaster)