CDK4 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)