PARP1 - HMGB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PARP1	ENSG00000143799	No diseases in record	OLAPARIB	DNA binding DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity protein binding transcription factor binding zinc ion binding enzyme binding protein kinase binding estrogen receptor binding identical protein binding histone deacetylase binding protein N-terminus binding NAD binding R-SMAD binding	Parp (D. melanogaster)
HMGB2	ENSG00000164104	No diseases in record	No drugs in record	four-way junction DNA binding enhancer sequence-specific DNA binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding drug binding DNA binding, bending protein domain specific binding chemoattractant activity transcription regulatory region DNA binding non-sequence-specific DNA binding, bending RAGE receptor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)