ABL1 - WT1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ABL1 ENSG00000097007 CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
nicotinate-nucleotide adenylyltransferase activity
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
SH3 domain binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
receptor binding
abl-1 (C. elegans)
Abl (D. melanogaster)
WT1 ENSG00000184937 Wilms tumour
desmoplastic small round cell tumour

No drugs in record

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
zinc ion binding
double-stranded methylated DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
hemi-methylated DNA-binding
C2H2 zinc finger domain binding
MIG1 (S. cerevisiae)
MIG2 (S. cerevisiae)
MIG3 (S. cerevisiae)