EZH2 - WT1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EZH2 ENSG00000106462 DLBCL

No drugs in record

RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
DNA binding
chromatin binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
histone methyltransferase activity (H3-K27 specific)
primary miRNA binding
promoter-specific chromatin binding
SET2 (S. cerevisiae)
lin-59 (C. elegans)
E(z) (D. melanogaster)
WT1 ENSG00000184937 Wilms tumour
desmoplastic small round cell tumour

No drugs in record

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
zinc ion binding
double-stranded methylated DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
hemi-methylated DNA-binding
C2H2 zinc finger domain binding
MIG1 (S. cerevisiae)
MIG2 (S. cerevisiae)
MIG3 (S. cerevisiae)