CASP8 - MAP2K5

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
MAP2K5	ENSG00000137764	No diseases in record	No drugs in record	protein kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding metal ion binding	PBS2 (S. cerevisiae)