TOP2B - PRMT8

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
PRMT8	ENSG00000111218	No diseases in record	No drugs in record	protein binding histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity identical protein binding protein homodimerization activity protein heterodimerization activity	HMT1 (S. cerevisiae) prmt-1 (C. elegans) Art1 (D. melanogaster)