ITCH - AXIN1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ITCH ENSG00000078747

No diseases in record

No drugs in record

ubiquitin-protein transferase activity
protein binding
ubiquitin-like protein transferase activity
ribonucleoprotein complex binding
CXCR chemokine receptor binding
ubiquitin protein ligase activity
RSP5 (S. cerevisiae)
wwp-1 (C. elegans)
Su(dx) (D. melanogaster)
AXIN1 ENSG00000103126 colorectal
endometrial
prostate
hepatocellular carcinoma
hepatoblastoma
sporadic medulloblastoma

No drugs in record

signal transducer activity
GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
receptor signaling complex scaffold activity
ubiquitin protein ligase binding
protein complex scaffold activity
identical protein binding
protein homodimerization activity
SMAD binding
armadillo repeat domain binding
I-SMAD binding
Axn (D. melanogaster)