MAPK1 - NOTCH1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAPK1	ENSG00000100030	CLL ovarian mixed germ cell tumour cervical carcinoma	No drugs in record	phosphotyrosine residue binding DNA binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding transcription factor binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity phosphatase binding mitogen-activated protein kinase kinase kinase binding identical protein binding	FUS3 (S. cerevisiae) KSS1 (S. cerevisiae) mpk-1 (C. elegans) rl (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)