ABL1 - AXIN1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ABL1 ENSG00000097007 CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
nicotinate-nucleotide adenylyltransferase activity
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
SH3 domain binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
receptor binding
abl-1 (C. elegans)
Abl (D. melanogaster)
AXIN1 ENSG00000103126 colorectal
endometrial
prostate
hepatocellular carcinoma
hepatoblastoma
sporadic medulloblastoma

No drugs in record

signal transducer activity
GTPase activator activity
protein binding
beta-catenin binding
enzyme binding
protein kinase binding
receptor signaling complex scaffold activity
ubiquitin protein ligase binding
protein complex scaffold activity
identical protein binding
protein homodimerization activity
SMAD binding
armadillo repeat domain binding
I-SMAD binding
Axn (D. melanogaster)