RAPGEF5 - JAK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAPGEF5	ENSG00000136237	No diseases in record	No drugs in record	Ras guanyl-nucleotide exchange factor activity Rap guanyl-nucleotide exchange factor activity GTP-dependent protein binding	epac-1 (C. elegans)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)