CBL - PDE4D

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)
PDE4D	ENSG00000113448	No diseases in record	AMLEXANOX APREMILAST DIPYRIDAMOLE DYPHYLLINE FLAVOXATE PENTOXIFYLLINE ROFLUMILAST THEOPHYLLINE THEOPHYLLINE GLYCINATE	3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity protein binding drug binding enzyme binding cAMP binding beta-2 adrenergic receptor binding ion channel binding metal ion binding ATPase binding scaffold protein binding	pde-4 (C. elegans) dnc (D. melanogaster)