JAK2 - KCNH1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
JAK2 ENSG00000096968 ALL
AML
MPN
CML
RUXOLITINIB
TOFACITINIB
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
interleukin-12 receptor binding
protein binding
ATP binding
protein C-terminus binding
protein kinase binding
heme binding
type 1 angiotensin receptor binding
acetylcholine receptor binding
histone kinase activity (H3-Y41 specific)
SH2 domain binding
histone binding
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
metal ion binding
peptide hormone receptor binding
hop (D. melanogaster)
KCNH1 ENSG00000143473

No diseases in record

DALFAMPRIDINE
DOFETILIDE
GUANIDINE
phosphorelay sensor kinase activity
delayed rectifier potassium channel activity
protein binding
calmodulin binding
protein kinase binding
identical protein binding
ion channel binding
protein heterodimerization activity
14-3-3 protein binding
phosphatidylinositol bisphosphate binding
cyclic nucleotide binding
eag (D. melanogaster)