ABL1 - SH2B3

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ABL1 ENSG00000097007 CML
ALL
T-ALL
BOSUTINIB
DASATINIB
IMATINIB
NILOTINIB
PONATINIB
REGORAFENIB
magnesium ion binding
DNA binding
actin monomer binding
nicotinate-nucleotide adenylyltransferase activity
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
SH3 domain binding
syntaxin binding
manganese ion binding
actin filament binding
mitogen-activated protein kinase binding
proline-rich region binding
receptor binding
abl-1 (C. elegans)
Abl (D. melanogaster)
SH2B3 ENSG00000111252 MPN
sAML
erythrocytosis
B-ALL

No drugs in record

signal transducer activity
protein binding
signaling adaptor activity

No GO terms in record