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PROX1 - ERBB4
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PROX1
ENSG00000117707
No diseases in record
No drugs in record
core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
protein binding
ligand-dependent nuclear receptor binding
transcription regulatory region DNA binding
DBD domain binding
LBD domain binding
pros-1 (C. elegans)
pros (D. melanogaster)
ERBB4
ENSG00000178568
melanoma
gastric
NSCLC
AFATINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
let-23 (C. elegans)
Egfr (D. melanogaster)