PROX1 - ERBB4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PROX1 ENSG00000117707

No diseases in record

No drugs in record

core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
protein binding
ligand-dependent nuclear receptor binding
transcription regulatory region DNA binding
DBD domain binding
LBD domain binding
pros-1 (C. elegans)
pros (D. melanogaster)
ERBB4 ENSG00000178568 melanoma
gastric
NSCLC
AFATINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
let-23 (C. elegans)
Egfr (D. melanogaster)