GSK3B - NOTCH1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
GSK3B ENSG00000082701

No diseases in record

LITHIUM CARBONATE
LITHIUM CITRATE
RNA polymerase II transcription factor binding
p53 binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
beta-catenin binding
kinase activity
protein kinase binding
ubiquitin protein ligase binding
protein kinase A catalytic subunit binding
tau-protein kinase activity
NF-kappaB binding
MRK1 (S. cerevisiae)
RIM11 (S. cerevisiae)
gsk-3 (C. elegans)
sgg (D. melanogaster)
gskt (D. melanogaster)
NOTCH1 ENSG00000148400 T-ALL
breast
bladder
skin SCC
lung SCC
head and neck SCC

No drugs in record

core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
enzyme inhibitor activity
receptor activity
Notch binding
calcium ion binding
protein binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
protein heterodimerization activity
N (D. melanogaster)