PKP2 - TP53

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PKP2	ENSG00000057294	No diseases in record	No drugs in record	molecular_function protein kinase C binding protein binding sodium channel regulator activity intermediate filament binding protein complex scaffold activity ion channel binding alpha-catenin binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cadherin binding involved in cell-cell adhesion transferase activity ATP binding nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity protein kinase activity kinase activity	jac-1 (C. elegans) p120ctn (D. melanogaster)
TP53	ENSG00000141510	breast colorectal lung sarcoma adrenocortical glioma Spitzoid tumour multiple other tumour types adrenocortical carcinoma	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter sequence-specific DNA binding RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protease binding p53 binding DNA binding chromatin binding damaged DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding copper ion binding protein binding ATP binding transcription factor binding zinc ion binding enzyme binding protein kinase binding protein phosphatase binding receptor tyrosine kinase binding ubiquitin protein ligase binding histone acetyltransferase binding identical protein binding sequence-specific DNA binding protein self-association transcription regulatory region DNA binding protein heterodimerization activity protein N-terminus binding chaperone binding protein phosphatase 2A binding	No GO terms in record