JAK2 - ARR3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
ARR3	ENSG00000120500	No diseases in record	No drugs in record	opsin binding protein binding phosphoprotein binding antiporter activity arsenite transmembrane transporter activity inorganic anion transmembrane transporter activity organic acid transmembrane transporter activity antimonite transmembrane transporter activity	Arr1 (D. melanogaster) krz (D. melanogaster) Arr2 (D. melanogaster)