PDGFRB - GNAQ

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
GNAQ	ENSG00000156052	uveal melanoma primary central nervous system melanocytic neoplasms	No drugs in record	GTPase activity signal transducer activity GTPase activator activity protein binding GTP binding G-protein beta/gamma-subunit complex binding type 2A serotonin receptor binding metal ion binding	GPA2 (S. cerevisiae)